|Application ||WB, E|
|Other Accession||NP_071429, 64106|
|Calculated MW||47819 Da|
|Other Names||Neuropeptide FF receptor 1, G-protein coupled receptor 147, RFamide-related peptide receptor OT7T022, NPFFR1, GPR147, NPFF1|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-NPFFR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis. Ubuka T, et al. PLoS One, 2009 Dec 22. PMID 20027225.
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Grupe A, et al. Am J Hum Genet, 2006 Jan. PMID 16385451.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Hinuma S, et al. Nat Cell Biol, 2000 Oct. PMID 11025660.
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