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Goat Anti-Npy2r (mouse) Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-Npy2r (mouse) Antibody AF1744a
    AF1744a (0.1 µg/ml) staining of Rat Brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49146
Other Accession NP_032757, 4887, 18167 (mouse), 66024 (rat)
Reactivity Human, Mouse, Rat
Predicted Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 42731 Da
Additional Information
Gene ID 4887
Other Names Neuropeptide Y receptor type 2, NPY2-R, NPY-Y2 receptor, Y2 receptor, NPY2R
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Npy2r (mouse) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NPY2R
Function Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra
Research Areas
Citations (0)

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NPY neuron-specific Y2 receptors regulate adipose tissue and trabecular bone but not cortical bone homeostasis in mice. Shi YC, et al. PLoS One, 2010 Jun 29. PMID 20613867.
New method of manometric measurement of gastroduodenal motility in conscious mice: effects of ghrelin and Y2 depletion. Tanaka R, et al. Am J Physiol Gastrointest Liver Physiol, 2009 Nov. PMID 20501433.
The central and basolateral amygdala are critical sites of neuropeptide Y/Y2 receptor-mediated regulation of anxiety and depression. Tasan RO, et al. J Neurosci, 2010 May 5. PMID 20445054.
NPY Y2 receptor agonist PYY(3-36) inhibits diarrhea by reducing intestinal fluid secretion and slowing colonic transit in mice. Moriya R, et al. Peptides, 2010 Apr. PMID 19925840.
Peripheral peptide YY inhibits propulsive colonic motor function through Y2 receptor in conscious mice. Wang L, et al. Am J Physiol Gastrointest Liver Physiol, 2010 Jan. PMID 19892938.

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$ 325.00
Cat# AF1744a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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