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PCK1 / PEPCKC (internal region) AntibodyPeptide-affinity purified goat antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AF1796a | 0.1mg 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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PCK1 / PEPCKC (internal region) Antibody - Product info | |
| Other Accession | NP_002582 |
| Reactivity | Human |
| Concentration | 100ug/200ul |
| Isotype | IgG |
PCK1 / PEPCKC (internal region) Antibody - Additional info | |
| Other Names PCK1; PEPCKC ; phosphoenolpyruvate carboxykinase 1 (soluble) ; MGC22652; PEPCK1; PEP carboxykinase; cytosolic phosphoenolpyruvate carboxykinase 1; phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase | |
| Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions PCK1 / PEPCKC (internal region) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
PCK1 / PEPCKC (internal region) Antibody - Application data
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AF1796a (0.5 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
PCK1 / PEPCKC (internal region) Antibody - Related products
AP8093a: PCK1 Antibody (N-term)
AP8093b: PCK1 Antibody (C-term)
BP8093a: PCK1 Antibody (N-term) Blocking Peptide
BP8093b: PCK1 Antibody (C-term) Blocking Peptide
AT3233a: PCK1 Antibody (monoclonal) (M01)
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BACKGROUND
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
REFERENCES
COMMON VARIANTS IN 40 GENES ASSESSED FOR DIABETES INCIDENCE AND RESPONSE TO METFORMIN AND LIFESTYLE INTERVENTIONS IN THE DIABETES PREVENTION PROGRAM. Jablonski KA, et al. Diabetes, 2010 Aug 3. PMID 20682687. Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086. Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Rua帽o G, et al. Pharmacogenomics, 2010 Jul. PMID 20602615. Intermediate phenotypes identify divergent pathways to Alzheimer's disease. Shulman JM, et al. PLoS One, 2010 Jun 21. PMID 20574532. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
