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PDE11A AntibodyPeptide-affinity purified goat antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AF1801a | 0.1mg 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
PDE11A Antibody - Product info | |
| Other Accession | NP_001070664 |
| Reactivity | Human |
| Concentration | 100ug/200ul |
| Isotype | IgG |
PDE11A Antibody - Additional info | |
| Other Names PDE11A; phosphodiesterase 11A ; FLJ23693; MGC133355; MGC133356; PPNAD2 ; cAMP and cGMP cyclic nucleotide phosphodiesterase 11A; cyclic nucleotide phosphodiesterase 11A; dual 3', 5'-cyclic-AMP and -GMP phosphodiesterase 11A | |
| Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions PDE11A Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
PDE11A Antibody - Application data
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AF1801a (1 µg/ml) staining of Human Prostate lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
PDE11A Antibody - Related products
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
REFERENCES
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. Poor replication of candidate genes for major depressive disorder using genome-wide association data. Bosker FJ, et al. Mol Psychiatry, 2010 Mar 30. PMID 20351714. Failure to replicate genetic associations with antidepressant treatment response in duloxetine-treated patients. Perlis RH, et al. Biol Psychiatry, 2010 Jun 1. PMID 20110084. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
