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Goat Anti-Perilipin (C Terminus) Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-Perilipin (C Terminus) Antibody AF1812a
    AF1812a (0.01 µg/ml) staining of Human Adipose lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IF - Goat Anti-Perilipin (C Terminus) Antibody AF1812a
    AF1812a staining of differentiated 3T3-L1 adipocytes. Data kindly provided by Prof. J. Granneman, Detroit, USA
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60240
Other Accession NP_002657, 5346, 25629 (rat)
Reactivity Human
Predicted Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 55990 Da
Additional Information
Gene ID 5346
Other Names Perilipin-1, Lipid droplet-associated protein, PLIN1, PERI, PLIN
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Perilipin (C Terminus) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLIN1
Synonyms PERI, PLIN
Function Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone- sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.
Cellular Location Endoplasmic reticulum. Lipid droplet. Note=Lipid droplet surface- associated
Tissue Location Adipocytes..
Research Areas
Citations (0)

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The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene.


Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Rua帽o G, et al. Pharmacogenomics, 2010 Jul. PMID 20602615.
Association of lifestyle factors, polymorphisms in adiponectin, perilipin and hormone sensitive lipase, and clinical markers in Japanese males. Sone Y, et al. J Nutr Sci Vitaminol (Tokyo), 2010. PMID 20495294.
Association study of 182 candidate genes in anorexia nervosa. Pinheiro AP, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jul. PMID 20468064.
Perilipin gene 1237 T > C polymorphism is not associated with obesity risk in northern Chinese Han adults. Hu DS, et al. Biomed Environ Sci, 2009 Oct. PMID 20163070.
Expression of perilipin and adipophilin in nonalcoholic fatty liver disease; relevance to oxidative injury and hepatocyte ballooning. Fujii H, et al. J Atheroscler Thromb, 2009. PMID 20032580.

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$ 325.00
Cat# AF1812a
(40 western blots)
Availability: 7-10 days
Bulk Size
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