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Goat Anti-PGAM1 / PGAM2 / PGAM4 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-PGAM1 / PGAM2 / PGAM4 Antibody AF1816a
    Antibody (0.03µg/ml) staining of Human Cerebellum (A) and Liver (B) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • WB - Goat Anti-PGAM1 / PGAM2 / PGAM4 Antibody AF1816a
    Antibody (0.03µg/ml) staining of Human Cerebellum (A) and Liver (B) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P18669
Other Accession NP_001025062, 5223, 5224, 441531
Reactivity Human
Predicted Mouse, Rat, Pig, Cow, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 28804 Da
Additional Information
Gene ID 5223
Other Names Phosphoglycerate mutase 1,,,, BPG-dependent PGAM 1, Phosphoglycerate mutase isozyme B, PGAM-B, PGAM1, PGAMA
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-PGAM1 / PGAM2 / PGAM4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PGAM1
Synonyms PGAMA
Function Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC (synthase) and EC (phosphatase), but with a reduced activity.
Tissue Location In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues
Research Areas
Citations (0)

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Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.


Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Manifesting heterozygotes in a Japanese family with a novel mutation in the muscle-specific phosphoglycerate mutase (PGAM-M) gene. Hadjigeorgiou GM, et al. Neuromuscul Disord, 1999 Oct. PMID 10545043.
The molecular genetic basis of muscle phosphoglycerate mutase (PGAM) deficiency. Tsujino S, et al. Am J Hum Genet, 1993 Mar. PMID 8447317.

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$ 325.00
Cat# AF1816a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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