Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   Goat Anti-PGRMC1 / MPR Antibody   

Goat Anti-PGRMC1 / MPR Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-PGRMC1 / MPR Antibody AF1818a
    AF1818a (0.1 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • WB - Goat Anti-PGRMC1 / MPR Antibody AF1818a
    HEK293 overexpressing Human PGRMC1 (RC201918) and probed with AF1818a (mock transfection in first lane), tested by Origene. Result obtained with a previous batch.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00264
Other Accession NP_006658, 10857, 53328 (mouse)
Reactivity Human
Predicted Mouse, Rat
Host Goat
Clonality Polyclonal
Concentration 0.5mg/ml
Isotype IgG
Calculated MW 21671 Da
Additional Information
Gene ID 10857
Other Names Membrane-associated progesterone receptor component 1, mPR, PGRMC1, HPR6.6, PGRMC
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-PGRMC1 / MPR Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HPR6.6, PGRMC
Function Receptor for progesterone.
Cellular Location Microsome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
Tissue Location Widely expressed, with highest expression in liver and kidney
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney.


Progesterone receptor membrane component 1 (Pgrmc1): a heme-1 domain protein that promotes tumorigenesis and is inhibited by a small molecule. Ahmed IS, et al. J Pharmacol Exp Ther, 2010 May. PMID 20164297. Progesterone receptor membrane component-1 regulates the development and Cisplatin sensitivity of human ovarian tumors in athymic nude mice. Peluso JJ, et al. Endocrinology, 2009 Nov. PMID 19797399. Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants. Menon R, et al. Reprod Biol Endocrinol, 2009 Jun 15. PMID 19527514. Progesterone activates a progesterone receptor membrane component 1-dependent mechanism that promotes human granulosa/luteal cell survival but not progesterone secretion. Peluso JJ, et al. J Clin Endocrinol Metab, 2009 Jul. PMID 19417032. Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. Velez DR, et al. Am J Obstet Gynecol, 2009 Feb. PMID 19019335.

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 325.00
Cat# AF1818a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions