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PHLPP2 AntibodyPeptide-affinity purified goat antibody

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AF1821a 0.1mg 400 ul 7-10 days $ 325.00 Add to cart
  • Specification
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PHLPP2 Antibody - Product info

Other AccessionNP_055835
ReactivityHuman
Concentration100ug/200ul
IsotypeIgG

PHLPP2 Antibody - Additional info

Other Names
PHLPP2; PHLPPL; PH domain and leucine rich repeat protein phosphatase-like ; KIAA0931
Format
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
PHLPP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

PHLPP2 Antibody - Application data

  • AF1821a (0.1 µg/ml) staining of Human Brain (Amygdala, Hippocampus, Substantia Nigra) lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

PHLPP2 Antibody - Related products

AP7799a: PHLPP2 Antibody (N-term)

AP7799b: PHLPP2 Antibody (C-term)

RI13966: PHLPP2 predesign siRNA

BP7799a: PHLPP2 Antibody (N-term) Blocking Peptide

AF1821a: PHLPP2 Antibody

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Provided below are standard protocols that you may find useful for product applications.

REFERENCES

Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis. Qiao M, et al. Mol Cell, 2010 May 28. PMID 20513427. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732. Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C. Brognard J, et al. J Biol Chem, 2009 May 29. PMID 19324870. Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms. Hirano I, et al. J Biol Chem, 2009 Aug 14. PMID 19261608.