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PINK1 AntibodyPeptide-affinity purified goat antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AF1830a | 0.1mg 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
PINK1 Antibody - Product info | |
| Other Accession | NP_115785 |
| Reactivity | Rat |
| Concentration | 100ug/200ul |
| Isotype | IgG |
PINK1 Antibody - Additional info | |
| Other Names PINK1; PTEN induced putative kinase 1 ; BRPK; FLJ27236; PARK6 ; protein kinase BRPK; serine/threonine-protein kinase PINK1 | |
| Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions PINK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
PINK1 Antibody - Application data
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AF1830a (1 µg/ml) staining of Rat Testis lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
PINK1 Antibody - Related products
AM6406a: PINK1 Antibody (Ascites)
AP6406a: PINK1 (PARK6) Antibody (N-term T133)
AP6406b: PINK1 (PARK6) Antibody (Center)
AP6406e: Park6 (PINK1)-D309.MT*
RI14010: PINK1 predesign siRNA
LY10497a: PINK1 Over-expression Lysate
BP6406a: PARK6 (PINK1) Antibody (N-term T133) Blocking Peptide
BP6406b: PARK6 (PINK1) Antibody (C-term E252) Blocking Peptide
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BACKGROUND
This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.
REFERENCES
Oxidative stress alters the regulatory control of p66Shc and Akt in PINK1 deficient cells. Maj MC, et al. Biochem Biophys Res Commun, 2010 Aug 27. PMID 20637729. Assessing the prevalence of PINK1 genetic variants in South African patients diagnosed with early- and late-onset Parkinson's disease. Keyser RJ, et al. Biochem Biophys Res Commun, 2010 Jul 16. PMID 20558144. Progression of subtle motor signs in PINK1 mutation carriers with mild dopaminergic deficit. Eggers C, et al. Neurology, 2010 Jun 1. PMID 20513816. Structural imaging in the presymptomatic stage of genetically determined parkinsonism. Reetz K, et al. Neurobiol Dis, 2010 Sep. PMID 20483373. Clinical and demographic characteristics of PINK1 mutation carriers--a meta-analysis. Kasten M, et al. Mov Disord, 2010 May 15. PMID 20461815.
