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Goat Anti-Radixin Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-Radixin Antibody AF1903a
    AF1903a (0.03 µg/ml) staining of Human Tonsil lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • WB - Goat Anti-Radixin Antibody AF1903a
    AF1903a (0.01 µg/ml) staining of NIH3T3 (A), HeLa (B), Jurkat (C), and A431 (D) lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35241
Other Accession NP_002897, 5962, 19684 (mouse), 315655 (rat)
Reactivity Human, Mouse, Rat
Predicted Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 68564 Da
Additional Information
Gene ID 5962
Other Names Radixin, RDX
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Radixin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RDX
Function Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
Cellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow Note=Highly concentrated in the undercoat of the cell-to-cell adherens junction and the cleavage furrow in the interphase and mitotic phase, respectively
Research Areas
Citations (0)

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Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses.


Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. Parisiadou L, et al. J Neurosci, 2009 Nov 4. PMID 19890007.
Regulation of NK cell trafficking by CD81. Kr脌mer B, et al. Eur J Immunol, 2009 Dec. PMID 19830727.
Evaluation of nine candidate genes in patients with normal tension glaucoma: a case control study. Wolf C, et al. BMC Med Genet, 2009 Sep 15. PMID 19754948.
Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.
LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation. Belkina NV, et al. Proc Natl Acad Sci U S A, 2009 Mar 24. PMID 19255442.

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$ 325.00
Cat# AF1903a
(40 western blots)
Availability: 7-10 days
Bulk Size
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