|Application ||WB, E|
|Other Accession||NP_848488, 10267, 51801 (mouse), 58965 (rat)|
|Calculated MW||16988 Da|
|Other Names||Receptor activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1, CRLR activity-modifying protein 1, RAMP1|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Ramp1 (C-Term., mouse) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Genetic enhancement of calcitonin gene-related Peptide-induced central sensitization to mechanical stimuli in mice. Marquez de Prado B, et al. J Pain, 2009 Sep. PMID 19628434.
Expression of the calcitonin receptor, calcitonin receptor-like receptor, and receptor activity modifying proteins during osteoclast differentiation. Granholm S, et al. J Cell Biochem, 2008 Jun 1. PMID 18384073.
Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice. Tsujikawa K, et al. Proc Natl Acad Sci U S A, 2007 Oct 16. PMID 17923674.
Interaction of receptor-activity-modifying protein1 with tubulin. Kunz TH, et al. Biochim Biophys Acta, 2007 Aug. PMID 17493758.
Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073.
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