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Goat Anti-RGS13 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-RGS13 Antibody AF1924a
    AF1924a (0.5 µg/ml) staining of Peripheral Blood Mononucleocyte lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14921
Other Accession NP_658912, 6003
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 19135 Da
Additional Information
Gene ID 6003
Other Names Regulator of G-protein signaling 13, RGS13, RGS13
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-RGS13 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RGS13
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)- alpha (By similarity).
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.


Genetic Variations in Regulator of G-Protein Signaling Genes as Susceptibility Loci for Second Primary Tumor/Recurrence in Head and Neck Squamous Cell Carcinoma. Wang J, et al. Carcinogenesis, 2010 Jul 12. PMID 20627871.
Association study of 182 candidate genes in anorexia nervosa. Pinheiro AP, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jul. PMID 20468064.
RGS13 controls g protein-coupled receptor-evoked responses of human mast cells. Bansal G, et al. J Immunol, 2008 Dec 1. PMID 19017978.
The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414.
RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization. Han JI, et al. J Leukoc Biol, 2006 Jun. PMID 16565322.

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$ 325.00
Cat# AF1924a
(40 western blots)
Availability: 7-10 days
Bulk Size
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