|Application ||WB, E|
|Other Accession||NP_739575, 80352, 171387 (rat)|
|Calculated MW||45525 Da|
|Other Names||RING finger protein 39, Protein HZFw, RNF39, HZFW|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-RNF39 / LIRF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in prolonged long term-potentiation (LTP) maintenance.|
|Tissue Location||Expressed in testis.|
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Provided below are standard protocols that you may find useful for product applications.
This gene lies within the major histocompatibility complex class I region on chromosome 6. Studies of a similar rat protein suggest that this gene encodes a protein that plays a role in an early phase of synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01. Cree BA, et al. PLoS One, 2010 Jun 25. PMID 20593013.
Common genetic variation and the control of HIV-1 in humans. Fellay J, et al. PLoS Genet, 2009 Dec. PMID 20041166.
High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. Barcellos LF, et al. PLoS Genet, 2009 Oct. PMID 19851445.
The HLA-B/-C haplotype block contains major determinants for host control of HIV. Trachtenberg E, et al. Genes Immun, 2009 Dec. PMID 19693088.
Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02). Limou S, et al. J Infect Dis, 2009 Feb 1. PMID 19115949.
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