|Application ||WB, E|
|Other Accession||NP_001139317, 6091, 19876 (mouse), 58946 (rat)|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||180930 Da|
|Other Names||Roundabout homolog 1, Deleted in U twenty twenty, H-Robo-1, ROBO1, DUTT1|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-ROBO1 / DUTT1 (Internal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Widely expressed, with exception of kidney.|
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