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Goat Anti-RPS19 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-RPS19 Antibody AF1946a
    AF1946a (0.1 µg/ml) staining of K562 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P39019
Other Accession NP_001013, 6223
Reactivity Human
Predicted Mouse, Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 16060 Da
Additional Information
Gene ID 6223
Other Names 40S ribosomal protein S19, RPS19
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-RPS19 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPS19
Function Required for pre-rRNA processing and maturation of 40S ribosomal subunits.
Cellular Location Nucleus. Note=Located more specifically in the nucleoli
Tissue Location Higher level expression is seen in the colon carcinoma tissue than normal colon tissue
Research Areas
Citations (0)

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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.


Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
Ribosomal protein S19 binds to its own mRNA with reduced affinity in Diamond-Blackfan anemia. Schuster J, et al. Blood Cells Mol Dis, 2010 Jun 15. PMID 20395159.
Mutations in the ribosomal protein genes in Japanese patients with Diamond-Blackfan anemia. Konno Y, et al. Haematologica, 2010 Aug. PMID 20378560.
A plasma protein indistinguishable from ribosomal protein S19: conversion to a monocyte chemotactic factor by a factor XIIIa-catalyzed reaction on activated platelet membrane phosphatidylserine in association with blood coagulation. Semba U, et al. Am J Pathol, 2010 Mar. PMID 20093496.
Genetic variants in the noncoding region of RPS19 gene in Diamond-Blackfan anemia: potential implications for phenotypic heterogeneity. Cr茅tien A, et al. Am J Hematol, 2010 Feb. PMID 20054847.

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$ 325.00
Cat# AF1946a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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