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Goat Anti-SH2D4A Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-SH2D4A Antibody AF1986a
    AF1986a (0.1 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H788
Other Accession NP_071354, 63898
Reactivity Human
Predicted Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 52727 Da
Additional Information
Gene ID 63898
Other Names SH2 domain-containing protein 4A, Protein SH(2)A, Protein phosphatase 1 regulatory subunit 38, SH2D4A, PPP1R38, SH2A
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-SH2D4A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SH2D4A
Synonyms PPP1R38, SH2A
Function Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
Cellular Location Cytoplasm. Note=Located at podocyte foot processes.
Tissue Location Ubiquitously expressed. Aberrantly expressed in some cancers.
Research Areas
Citations (0)

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Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
SH2D4A regulates cell proliferation via the ERalpha/PLC-gamma/PKC pathway. Li T, et al. BMB Rep, 2009 Aug 31. PMID 19712589.
An empirical framework for binary interactome mapping. Venkatesan K, et al. Nat Methods, 2009 Jan. PMID 19060904.
Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells. Lapinski PE, et al. J Immunol, 2008 Aug 1. PMID 18641339.
Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.

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$ 325.00
Cat# AF1986a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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