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Goat Anti-SMAD9 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-SMAD9 Antibody AF2005a
    AF2005a (0.3 µg/ml) staining of Human Skin lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • EIA - Goat Anti-SMAD9 Antibody AF2005a
    AF2005a (1.5ug/ml) as the reporter with EB002022 as the capture rabbit antibody (2.5ug/ml).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15198
Other Accession NP_005896, 4093
Reactivity Human
Predicted Mouse, Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 52493 Da
Additional Information
Gene ID 4093
Other Names Mothers against decapentaplegic homolog 9, MAD homolog 9, Mothers against DPP homolog 9, Madh6, SMAD family member 9, SMAD 9, Smad9, SMAD9, MADH6, MADH9
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-SMAD9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SMAD9
Synonyms MADH6, MADH9
Function Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).
Cellular Location Cytoplasm. Nucleus. Note=In the cytoplasm in the absence of ligand Migration to the nucleus when complexed with SMAD4 (By similarity).
Tissue Location Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.


Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
BMP4-Smad signaling pathway mediates adriamycin-induced premature senescence in lung cancer cells. Su D, et al. J Biol Chem, 2009 May 1. PMID 19269967.
Serotonin induces Rho/ROCK-dependent activation of Smads 1/5/8 in pulmonary artery smooth muscle cells. Liu Y, et al. FASEB J, 2009 Jul. PMID 19244313.
A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension. Shintani M, et al. J Med Genet, 2009 May. PMID 19211612.
Holding their own: the noncanonical roles of Smad proteins. Hoover LL, et al. Sci Signal, 2008 Nov 18. PMID 19018011.

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$ 325.00
Cat# AF2005a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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