Goat Anti-SNX19 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q92543 |
Other Accession | NP_055573, 399979 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 100ug/200ul |
Isotype | IgG |
Calculated MW | 108598 Da |
Gene ID | 399979 |
---|---|
Other Names | Sorting nexin-19, SNX19, KIAA0254 |
Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-SNX19 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SNX19 |
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Synonyms | KIAA0254 |
Function | Plays a role in intracellular vesicle trafficking and exocytosis (PubMed:24843546). May play a role in maintaining insulin- containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion (PubMed:24843546). Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) (By similarity). |
Cellular Location | Early endosome membrane {ECO:0000250|UniProtKB:Q6P4T1}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q6P4T1}; Cytoplasmic side {ECO:0000250|UniProtKB:Q6P4T1}. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side |
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References
Polymorphisms associated with both noncardioembolic stroke and coronary heart disease: vienna stroke registry. Luke MM, et al. Cerebrovasc Dis, 2009. PMID 19752551.
The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors. Landa I, et al. PLoS Genet, 2009 Sep. PMID 19730683.
Gene variants associated with ischemic stroke: the cardiovascular health study. Luke MM, et al. Stroke, 2009 Feb. PMID 19023099.
Five common gene variants identify elevated genetic risk for coronary heart disease. Bare LA, et al. Genet Med, 2007 Oct. PMID 18073581.
Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. Shiffman D, et al. Arterioscler Thromb Vasc Biol, 2008 Jan. PMID 17975119.
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