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Goat Anti-Spinesin / TMPRSS5 Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-Spinesin / TMPRSS5 Antibody AF2032a
    AF2032a staining (0.5 µg/ml) of Human Brain (Cerortex) lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.
    detail
  • IHC - Goat Anti-Spinesin / TMPRSS5 Antibody AF2032a
    AF2032a (5 µg/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
    detail
  • IHC - Goat Anti-Spinesin / TMPRSS5 Antibody AF2032a
    AF2032a (5 µg/ml) staining of paraffin embedded Human Small Intestine. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession Q9H3S3
Other Accession NP_110397, 80975
Reactivity Human, Mouse, Rat
Predicted Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 49560 Da
Additional Information
Gene ID 80975
Other Names Transmembrane protease serine 5, 3.4.21.-, Spinesin, TMPRSS5
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Spinesin / TMPRSS5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMPRSS5
Function May play a role in hearing.
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord
Research Areas
Citations (0)
citation

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Background

This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes.

References

ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts. Mohan S, et al. Biochemistry, 2002 Dec 24. PMID 12484779.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Spinesin/TMPRSS5, a novel transmembrane serine protease, cloned from human spinal cord. Yamaguchi N, et al. J Biol Chem, 2002 Mar 1. PMID 11741986.

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$ 341.00
Cat# AF2032a
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Availability: 7-10 days
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