|Application ||WB, IHC, E|
|Other Accession||NP_110397, 80975|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||49560 Da|
|Other Names||Transmembrane protease serine 5, 3.4.21.-, Spinesin, TMPRSS5|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Spinesin / TMPRSS5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in hearing.|
|Cellular Location||Cell membrane; Single-pass type II membrane protein|
|Tissue Location||Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes.
ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts. Mohan S, et al. Biochemistry, 2002 Dec 24. PMID 12484779.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Spinesin/TMPRSS5, a novel transmembrane serine protease, cloned from human spinal cord. Yamaguchi N, et al. J Biol Chem, 2002 Mar 1. PMID 11741986.
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