|Application ||WB, IHC, E|
|Other Accession||NP_110397, 80975|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||49560 Da|
|Other Names||Transmembrane protease serine 5, 3.4.21.-, Spinesin, TMPRSS5|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Spinesin / TMPRSS5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in hearing.|
|Cellular Location||Cell membrane; Single-pass type II membrane protein|
|Tissue Location||Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes.
ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts. Mohan S, et al. Biochemistry, 2002 Dec 24. PMID 12484779.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Spinesin/TMPRSS5, a novel transmembrane serine protease, cloned from human spinal cord. Yamaguchi N, et al. J Biol Chem, 2002 Mar 1. PMID 11741986.
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