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Goat Anti-STX6 Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-STX6 Antibody AF2049a
    AF2049a (0.3 µg/ml) staining of human lymph node lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
  • WB - Goat Anti-STX6 Antibody AF2049a
    HEK293 overexpressing Human STX6 (RC202951) and probed with AF2049a (mock transfection in first lane), tested by Origene.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O43752
Other Accession NP_005810, 10228, 58244 (mouse), 60562 (rat)
Reactivity Human
Predicted Mouse, Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 29176 Da
Additional Information
Gene ID 10228
Other Names Syntaxin-6, STX6
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-STX6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STX6
Function SNARE promoting movement of transport vesicles to target membranes. Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking. Together with SNARE STX12, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway.
Cellular Location Golgi apparatus membrane; Single-pass type IV membrane protein. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q63635}; Single-pass type IV membrane protein. Recycling endosome membrane {ECO:0000250|UniProtKB:Q63635}; Single-pass type IV membrane protein
Research Areas
Citations (0)
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References

Syntaxin 6 and CAL mediate the degradation of the cystic fibrosis transmembrane conductance regulator. Cheng J, et al. Mol Biol Cell, 2010 Apr 1. PMID 20130090.
Syntaxin 6, a regulator of the protein trafficking machinery and a target of the p53 family, is required for cell adhesion and survival. Zhang Y, et al. J Biol Chem, 2008 Nov 7. PMID 18779328.
The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414.
MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking. Nakamura N, et al. Mol Biol Cell, 2005 Apr. PMID 15689499.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

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$ 341.00
Cat# AF2049a
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