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Goat Anti-SV2A Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-SV2A Antibody AF2052a
    AF2052a (0.3 µg/ml) staining of rat brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7L0J3
Other Accession NP_055664, 9900, 64051 (mouse), 117559 (rat)
Reactivity Rat
Predicted Human, Mouse, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 82695 Da
Additional Information
Gene ID 9900
Other Names Synaptic vesicle glycoprotein 2A, SV2A, KIAA0736
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-SV2A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SV2A
Synonyms KIAA0736
Function Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).
Cellular Location Cell junction, synapse {ECO:0000250|UniProtKB:Q9JIS5}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q02563}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q02563} Note=Enriched in chromaffin granules, not present in adrenal microsomes. Associated with both insulin granules and synaptic- like microvesicles in insulin-secreting cells of the pancreas (By similarity). Colocalizes with ATP2B1 at photoreceptor synaptic terminals. {ECO:0000250|UniProtKB:Q02563, ECO:0000250|UniProtKB:Q9JIS5}
Research Areas
Citations (0)

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Expression of synaptic vesicle protein 2A in epilepsy-associated brain tumors and in the peritumoral cortex. de Groot M, et al. Neuro Oncol, 2010 Mar. PMID 20167814.
Botulinum toxin type A inhibits the growth of LNCaP human prostate cancer cells in vitro and in vivo. Karsenty G, et al. Prostate, 2009 Aug 1. PMID 19399787.
Expression patterns of synaptic vesicle protein 2A in focal cortical dysplasia and TSC-cortical tubers. Toering ST, et al. Epilepsia, 2009 Jun. PMID 19220410.
No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy. Lynch JM, et al. Epilepsy Res, 2009 Jan. PMID 18977120.
Synaptic vesicle protein 2 binds adenine nucleotides. Yao J, et al. J Biol Chem, 2008 Jul 25. PMID 18524768.

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$ 325.00
Cat# AF2052a
(40 western blots)
Availability: 7-10 days
Bulk Size
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