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Goat Anti-TM4SF3 / TSPAN8 Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-TM4SF3 / TSPAN8 Antibody AF2094a
    AF2094a (0.01 µg/ml) staining of Human Colon lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P19075
Other Accession NP_004607, 7103
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 26044 Da
Additional Information
Gene ID 7103
Other Names Tetraspanin-8, Tspan-8, Transmembrane 4 superfamily member 3, Tumor-associated antigen CO-029, TSPAN8, TM4SF3
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-TM4SF3 / TSPAN8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TSPAN8
Synonyms TM4SF3
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Gastric, colon, rectal, and pancreatic carcinomas.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.

References

Obesity and diabetes genetic variants associated with gestational weight gain. Stuebe AM, et al. Am J Obstet Gynecol, 2010 Sep. PMID 20816152.
Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. Fontaine-Bisson B, et al. Diabetologia, 2010 Oct. PMID 20571754.
Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight. Andersson EA, et al. Diabetologia, 2010 Sep. PMID 20490451.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Wellcome Trust Case Control Consortium, et al. Nature, 2010 Apr 1. PMID 20360734.

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$ 341.00
Cat# AF2094a
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Availability: 7-10 days
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