|Application ||WB, E|
|Other Accession||NP_002344, 4070, 56753 (mouse)|
|Predicted||Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||35709 Da|
|Other Names||Tumor-associated calcium signal transducer 2, Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733-1, TACSTD2, GA733-1, M1S1, TROP2|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-TROP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GA733-1, M1S1, TROP2|
|Function||May function as a growth factor receptor.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Placenta, pancreatic carcinoma cell lines.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.
Expression of the GA733 gene family and its relationship to prognosis in pulmonary adenocarcinoma. Kobayashi H, et al. Virchows Arch, 2010 Jul. PMID 20473768.
Identification and characterization of a novel TACSTD2 mutation in gelatinous drop-like corneal dystrophy. Paliwal P, et al. Mol Vis, 2010 Apr 28. PMID 20454699.
Trop-2 overexpression as an independent marker for poor overall survival in ovarian carcinoma patients. Bignotti E, et al. Eur J Cancer, 2010 Mar. PMID 20060709.
A novel TACSTD2 mutation identified in two Chinese brothers with gelatinous drop-like corneal dystrophy. Jing Y, et al. Mol Vis, 2009 Aug 14. PMID 19693293.
[Expression of TROP2 mRNA in left-sided and right-sided colon cancer and its clinical significance] Xu KY, et al. Zhonghua Wei Chang Wai Ke Za Zhi, 2009 May. PMID 19434540.
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