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Goat Anti-TROP2 Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-TROP2 Antibody AF2114a
    AF2114a (0.2 µg/ml) staining of Human Prostate lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P09758
Other Accession NP_002344, 4070, 56753 (mouse)
Reactivity Human
Predicted Mouse, Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 35709 Da
Additional Information
Gene ID 4070
Other Names Tumor-associated calcium signal transducer 2, Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733-1, TACSTD2, GA733-1, M1S1, TROP2
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-TROP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TACSTD2
Synonyms GA733-1, M1S1, TROP2
Function May function as a growth factor receptor.
Cellular Location Membrane; Single-pass type I membrane protein.
Tissue Location Placenta, pancreatic carcinoma cell lines.
Research Areas
Citations (0)
citation

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Background

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

References

Expression of the GA733 gene family and its relationship to prognosis in pulmonary adenocarcinoma. Kobayashi H, et al. Virchows Arch, 2010 Jul. PMID 20473768.
Identification and characterization of a novel TACSTD2 mutation in gelatinous drop-like corneal dystrophy. Paliwal P, et al. Mol Vis, 2010 Apr 28. PMID 20454699.
Trop-2 overexpression as an independent marker for poor overall survival in ovarian carcinoma patients. Bignotti E, et al. Eur J Cancer, 2010 Mar. PMID 20060709.
A novel TACSTD2 mutation identified in two Chinese brothers with gelatinous drop-like corneal dystrophy. Jing Y, et al. Mol Vis, 2009 Aug 14. PMID 19693293.
[Expression of TROP2 mRNA in left-sided and right-sided colon cancer and its clinical significance] Xu KY, et al. Zhonghua Wei Chang Wai Ke Za Zhi, 2009 May. PMID 19434540.

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$ 341.00
Cat# AF2114a
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Availability: 7-10 days
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