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Goat Anti-Vitamin D-binding protein / GC Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-Vitamin D-binding protein / GC Antibody AF2147a
    AF2147a (0.03 µg/ml) staining of Lung lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P02774
Other Accession NP_000574, 2638
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 52964 Da
Additional Information
Gene ID 2638
Other Names Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, GC
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Vitamin D-binding protein / GC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GC
Function Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
Cellular Location Secreted.
Tissue Location Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine
Research Areas
Citations (0)

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Background

The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues.

References

Association of vitamin D binding protein variants with susceptibility to chronic obstructive pulmonary disease. Shen LH, et al. J Int Med Res, 2010 May-Jun. PMID 20819447.
Vitamin D-binding protein polymorphisms are not associated with development of (multiple) basal cell carcinomas. Flohil SC, et al. Exp Dermatol, 2010 Aug 31. PMID 20812960.
High-density polymorphisms analysis of 23 candidate genes for association with bone mineral density. Giroux S, et al. Bone, 2010 Jul 30. PMID 20654748.
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
Dengue hemorrhagic fever is associated with polymorphisms in JAK1. Silva LK, et al. Eur J Hum Genet, 2010 Jun 30. PMID 20588308.

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$ 335.00
Cat# AF2147a
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