|Application ||WB, E|
|Other Accession||NP_056520, 27352, 105835 (mouse), 362963 (rat)|
|Predicted||Mouse, Rat, Dog|
|Calculated MW||85354 Da|
|Other Names||Small G protein signaling modulator 3, Merlin-associated protein, RUN and TBC1 domain-containing protein 3, Rab-GTPase-activating protein-like protein, RabGAPLP, SGSM3 (HGNC:25228)|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-RUTBC3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a cooperative role in NF2-mediated growth suppression of cells.|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. Estrada K, et al. Hum Mol Genet, 2009 Sep 15. PMID 19570815.
Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity. Ishibashi K, et al. Genes Cells, 2009 Jan. PMID 19077034.
Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway. Yang H, et al. Genomics, 2007 Aug. PMID 17509819.
Novel rab GAP-like protein, CIP85, interacts with connexin43 and induces its degradation. Lan Z, et al. Biochemistry, 2005 Feb 22. PMID 15709751.
MAP, a protein interacting with a tumor suppressor, merlin, through the run domain. Lee IK, et al. Biochem Biophys Res Commun, 2004 Dec 17. PMID 15541357.
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