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MTMR1 (isoform 1) Antibody (C-Term)

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
E
Primary Accession Q13613
Other Accession NP_003819.1, 8776
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 74678 Da
Additional Information
Gene ID 8776
Other Names Myotubularin-related protein 1, Phosphatidylinositol-3-phosphate phosphatase, 3.1.3.64, MTMR1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMTMR1 (isoform 1) Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTMR1 (HGNC:7449)
Function Lipid phosphatase that has high specificity for phosphatidylinositol 3-phosphate and has no activity with phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)- bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate (PubMed:11733541, PubMed:27018598). Activity with phosphatidylinositol (3,5)-bisphosphate is controversial; it has been shown by PubMed:27018598, while PubMed:11733541 find no activity with this substrate.
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q9Z2C4}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9Z2C4}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9Z2C4}. Cytoplasm {ECO:0000250|UniProtKB:Q9Z2C4}
Research Areas
Citations (0)
citation

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Background

Please note this will only recognise Human isoform 1 (NP_003819.1), not isoform 2 (NP_789746).

References

A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast. Laporte J, Hu LJ, Kretz C, Mandel JL, Kioschis P, Coy JF, Klauck SM, Poustka A, Dahl N. Nat Genet 1996 Jun;13(2):175-82 PMID: 8640223

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$ 216.00
Cat# AF2249a
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