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Cyt19 / AS3MT Antibody (N-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC, E |
|---|---|
| Primary Accession | Q9HBK9 |
| Other Accession | NP_065733.2, 57412 |
| Predicted | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 41748 Da |
| Gene ID | 57412 |
|---|---|
| Other Names | Arsenite methyltransferase, 2.1.1.137, Methylarsonite methyltransferase, S-adenosyl-L-methionine:arsenic(III) methyltransferase, AS3MT, CYT19 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Cyt19 / AS3MT Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AS3MT |
|---|---|
| Synonyms | CYT19 |
| Function | Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals (PubMed:16407288, PubMed:25997655). It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2 (PubMed:16407288, PubMed:25997655). Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH (PubMed:16407288, PubMed:25997655). |
| Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q8VHT6} |
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Provided below are standard protocols that you may find useful for product applications.
References
A novel S-adenosyl-L-methionine:arsenic(III) methyltransferase from rat liver cytosol. Lin S, Shi Q, Nix FB, Styblo M, Beck MA, Herbin-Davis KM, Hall LL, Simeonsson JB, Thomas DJ. J Biol Chem. 2002 Mar 29;277(13):10795-803. PMID: 11790780
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