|Other Accession||AAK15343.1, 27443|
|Calculated MW||164213 Da|
|Other Names||Cat eye syndrome critical region protein 2, CECR2, KIAA1740|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CECR2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis.|
|Tissue Location||Highly expressed in skeletal muscle, thymus, placenta and lung. Expressed at lower level in brain, heart, colon, spleen, kidney|
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Provided below are standard protocols that you may find useful for product applications.
The peptide sequence used (from AAK15343.1) differs by one residue from the RefSeq entry (XP_931107.2). It is not known whether this difference is due to a sequencing error or polymophism but the antibody is expected to recognize both sequences.
Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere. Footz TK, Brinkman-Mills P, Banting GS, Maier SA, Riazi MA, Bridgland L, Hu S, Birren B, Minoshima S, Shimizu N, Pan H, Nguyen T, Fang F, Fu Y, Ray L, Wu H, Shaull S, Phan S, Yao Z, Chen F, Huan A, Hu P, Wang Q, Loh P, Qi S, Roe BA, McDermid HE. Genome Res. 2001 Jun;11(6):1053-70. PMID: 11381032
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