|Other Accession||NP_055864.2, 66008|
|Predicted||Human, Mouse, Rat, Pig, Cow|
|Calculated MW||101419 Da|
|Other Names||Trafficking kinesin-binding protein 2, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein, TRAK2, ALS2CR3, KIAA0549|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ALS2CR3 / GRIF1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.|
|Cellular Location||Cytoplasm. Early endosome. Mitochondrion. Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity)|
|Tissue Location||Widely expressed, with highest expression in heart|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2. Hadano S, Yanagisawa Y, Skaug J, Fichter K, Nasir J, Martindale D, Koop BF, Scherer SW, Nicholson DW, Rouleau GA, Ikeda J, Hayden MR. Genomics. 2001 Jan 15;71(2):200-13. PMID: 11161814
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