|Application ||WB, E|
|Other Accession||NP_908973.1, NP_908974.1, NP_908975.1, 84675, 381485 (mouse), 365751 (rat)|
|Predicted||Rat, Pig, Dog|
|Calculated MW||60466 Da|
|Other Names||Tripartite motif-containing protein 55, Muscle-specific RING finger protein 2, MuRF-2, MuRF2, RING finger protein 29, TRIM55, MURF2, RNF29|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MURF2 / TRIM55 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May regulate gene expression and protein turnover in muscle cells.|
|Cellular Location||Cytoplasm. Nucleus. Note=Nuclear under atrophic conditions and upon mechanical signals. Localizes to the sarcomeric M-band in cardiomyocytes. Colocalizes in part with microtubules (By similarity).|
|Tissue Location||Highly expressed in muscle. Low-level expression in liver.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize isoforms 1, 3 and 4 (NP_908973.1, NP_908974.1and NP_908975.1 resp.).
Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain. Centner T, Yano J, Kimura E, McElhinny AS, Pelin K, Witt CC, Bang ML, Trombitas K, Granzier H, Gregorio CC, Sorimachi H, Labeit S. J Mol Biol. 2001 Mar 2;306(4):717-26. PMID: 11243782
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