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SNX18 / SNAG1 Antibody (C-Term)

Peptide-affinity purified goat antibody

  • WB - SNX18 / SNAG1 Antibody (C-Term) AF2327a
    AF2327a (1 µg/ml) staining of A549 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96RF0
Other Accession NP_443102.2, 112574
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 68894 Da
Additional Information
Gene ID 112574
Other Names Sorting nexin-18, SH3 and PX domain-containing protein 3B, Sorting nexin-associated Golgi protein 1, SNX18, SH3PXD3B, SNAG1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNX18 / SNAG1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNX18
Synonyms SH3PXD3B, SNAG1
Function Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
Cellular Location Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin- coated pits at a late stage of clathrin-coated vesicle formation
Research Areas
Citations (0)

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A large family of endosome-localized proteins related to sorting nexin 1. Teasdale RD, Loci D, Houghton F, Karlsson L, Gleeson PA. Biochem J. 2001 Aug 15;358(Pt 1):7-16. PMID: 11485546

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$ 325.00
Cat# AF2327a
(40 western blots)
Availability: 7-10 days
Bulk Size
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