|Application ||WB, E|
|Other Accession||NP_061170.2, 55521, 28105 (mouse)|
|Calculated MW||83013 Da|
|Other Names||E3 ubiquitin-protein ligase TRIM36, 6.3.2.-, RING finger protein 98, Tripartite motif-containing protein 36, Zinc-binding protein Rbcc728, TRIM36, RBCC728, RNF98|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRIM36 / RNF98 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation. May play a role in the acrosome reaction and fertilization (By similarity).|
|Cellular Location||Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome. Cytoplasm, cytoskeleton. Note=Found in the acrosomal region of elongated spermatids and mature sperm.|
|Tissue Location||Highly expressed in testis, prostate and brain. Weakly expressed in kidney, lung and heart|
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Provided below are standard protocols that you may find useful for product applications.
The tripartite motif family identifies cell compartments. Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A. EMBO J. 2001 May 1;20(9):2140-51. PMID: 11331580
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