|Application ||IHC, E|
|Other Accession||NP_036320.2, NP_658982.1, 2299|
|Calculated MW||40973 Da|
|Other Names||Forkhead box protein I1, Forkhead-related protein FKHL10, Forkhead-related transcription factor 6, FREAC-6, Hepatocyte nuclear factor 3 forkhead homolog 3, HFH-3, HNF-3/fork-head homolog 3, FOXI1, FKHL10, FREAC6|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FOXI1 / FKHL10 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity).|
|Tissue Location||Expressed in kidney.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognise both reported human isoforms (NP_036320.2; NP_658982.1).
Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending. Pierrou S, Hellqvist M, Samuelsson L, Enerback S, Carlsson P. EMBO J. 1994 Oct 17;13(20):5002-12. PMID: 7957066
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