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FOXI1 / FKHL10 Antibody (C-Term)

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC, E
Primary Accession Q12951
Other Accession NP_036320.2, NP_658982.1, 2299
Reactivity Human, Mouse
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 40973 Da
Additional Information
Gene ID 2299
Other Names Forkhead box protein I1, Forkhead-related protein FKHL10, Forkhead-related transcription factor 6, FREAC-6, Hepatocyte nuclear factor 3 forkhead homolog 3, HFH-3, HNF-3/fork-head homolog 3, FOXI1, FKHL10, FREAC6
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFOXI1 / FKHL10 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXI1
Synonyms FKHL10, FREAC6
Function Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed in kidney.
Research Areas
Citations (0)
citation

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Background

This antibody is expected to recognise both reported human isoforms (NP_036320.2; NP_658982.1).

References

Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending. Pierrou S, Hellqvist M, Samuelsson L, Enerback S, Carlsson P. EMBO J. 1994 Oct 17;13(20):5002-12. PMID: 7957066

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$ 341.00
Cat# AF2348a
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