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BCOR / BCL6 co-repressor Antibody (N-Term)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6W2J9
Other Accession NP_060215.4, NP_001116855.1, NP_001116856.1, NP_001116857.1, 54880, 71458 (mouse)
Predicted Human, Mouse, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 192189 Da
Additional Information
Gene ID 54880
Other Names BCL-6 corepressor, BCoR, BCOR, KIAA1575
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBCOR / BCL6 co-repressor Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA1575
Function Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence- specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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This antibody is expected to recognise all reported isoforms. Variants (NP_060215.4; NP_001116855.1) encode the same isoform.


The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor. Tang TT, Dowbenko D, Jackson A, Toney L, Lewin DA, Dent AL, Lasky LA. J Biol Chem. 2002 Apr 19;277(16):14255-65. Epub 2002 Jan 02. PMID: 11777915

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$ 325.00
Cat# AF2350a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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