|Other Accession||NP_001032208.1, NP_055729.2, 116987|
|Calculated MW||94470 Da|
|Other Names||Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1, AGAP-1, Centaurin-gamma-2, Cnt-g2, GTP-binding and GTPase-activating protein 1, GGAP1, AGAP1, CENTG2, KIAA1099|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CENTG2 / AGAP1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.|
|Cellular Location||Cytoplasm. Note=Associates with the endocytic compartment|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognise both reported isoforms.
AGAP1, an Endosome-associated, Phosphoinositide-dependent ADP-ribosylation Factor GTPase-activating Protein That Affects Actin Cytoskeleton. Nie Z, Stanley KT, Stauffer S, Jacques KM, Hirsch DS, Takei J, Randazzo PA. J Biol Chem. 2002 Dec 13;277(50):48965-75. PMID: 12388557
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