Dispatched homolog 1 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IF, E |
---|---|
Primary Accession | Q96F81 |
Other Accession | NP_116279.2, 84976 |
Reactivity | Human |
Predicted | Mouse, Rat, Pig |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 170934 Da |
Gene ID | 84976 |
---|---|
Other Names | Protein dispatched homolog 1, DISP1, DISPA |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Dispatched homolog 1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DISP1 |
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Synonyms | DISPA |
Function | Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal (By similarity). Synergizes with SCUBE2 to cause an increase in SHH secretion (PubMed:22902404). |
Cellular Location | Membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
References
Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells. Burke R, Nellen D, Bellotto M, Hafen E, Senti KA, Dickson BJ, Basler K. Cell. 1999 Dec 23;99(7):803-15. PMID: 10619433
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