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EndoNEDD4 / NEDL2 Antibody (N-Term)

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
E
Primary Accession Q9P2P5
Other Accession NP_065811.1, 57520, 227106 (mouse)
Predicted Human, Mouse, Rat, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 175769 Da
Additional Information
Gene ID 57520
Other Names E3 ubiquitin-protein ligase HECW2, 6.3.2.-, HECT, C2 and WW domain-containing protein 2, NEDD4-like E3 ubiquitin-protein ligase 2, HECW2, KIAA1301, NEDL2
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEndoNEDD4 / NEDL2 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HECW2
Synonyms KIAA1301, NEDL2
Function E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487). Involved in the regulation of mitotic metaphase/anaphase transition (PubMed:24163370).
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, spindle
Tissue Location Predominantly expressed in adult brain, lung and heart.
Research Areas
Citations (0)
citation

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References

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O. DNA Res. 2000 Feb 28;7(1):65-73. PMID: 10718198

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$ 341.00
Cat# AF2418a
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