|Other Accession||NP_004200.2, 9143|
|Predicted||Human, Rat, Dog|
|Calculated MW||24555 Da|
|Other Names||Synaptogyrin-3, SYNGR3|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Synaptogyrin 3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the positive regulation of dopamine transporter activity. Probably facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, allowing a more efficient loading of the vesicles with extracellular dopamine after release (By similarity).|
|Cellular Location||Membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Cell junction, synapse. Note=Found at the neuromuscular synapses.|
|Tissue Location||Expressed in brain and placenta.|
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Provided below are standard protocols that you may find useful for product applications.
SV2B regulates synaptotagmin 1 by direct interaction. Lazzell DR, Belizaire R, Thakur P, Sherry DM, Janz R. J Biol Chem. 2004 Dec 10;279(50):52124-31. Epub 2004 Dec 10. PMID: 15466855
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