|Application ||WB, E|
|Other Accession||NP_001516.1, 3061|
|Predicted||Mouse, Rat, Dog, Sheep|
|Calculated MW||47536 Da|
|Other Names||Orexin receptor type 1, Ox-1-R, Ox1-R, Ox1R, Hypocretin receptor type 1, HCRTR1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Orexin receptor 1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Orexin loss in Huntington's disease. Petersen A, Gil J, Maat-Schieman ML, Bjorkqvist M, Tanila H, Araujo IM, Smith R, Popovic N, Wierup N, Norlen P, Li JY, Roos RA, Sundler F, Mulder H, Brundin P. Hum Mol Genet. 2005 Jan 1;14(1):39-47. Epub 2004 Nov 03. PMID: 15525658
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