|Other Accession||NP_443142.1, 114798|
|Predicted||Human, Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||77735 Da|
|Other Names||SLIT and NTRK-like protein 1, Leucine-rich repeat-containing protein 12, SLITRK1, KIAA1910, LRRC12|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLITRK1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Enhances neuronal dendrite outgrowth.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed predominantly in the frontal lobe of the cerebral cortex of the brain. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.|
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Sequence variants in SLITRK1 are associated with Tourette's syndrome. Abelson JF, Kwan KY, O'Roak BJ, Baek DY, Stillman AA, Morgan TM, Mathews CA, Pauls DL, Rasin MR, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, Dure LS 4th, Kurlan R, Singer HS, Gilbert DL, Farhi A, Louvi A, Lifton RP, Sestan N, St Science. 2005 Oct 14;310(5746):317-20. PMID: 16224024
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