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SLITRK1 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q96PX8 |
| Other Accession | NP_443142.1, 114798 |
| Predicted | Human, Mouse, Rat, Pig, Dog, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 77735 Da |
| Gene ID | 114798 |
|---|---|
| Other Names | SLIT and NTRK-like protein 1, Leucine-rich repeat-containing protein 12, SLITRK1, KIAA1910, LRRC12 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SLITRK1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLITRK1 |
|---|---|
| Synonyms | KIAA1910, LRRC12 |
| Function | It is involved in synaptogenesis and promotes excitatory synapse differentiation (PubMed:27273464, PubMed:27812321). Enhances neuronal dendrite outgrowth (PubMed:16224024, PubMed:19640509). |
| Cellular Location | Membrane; Single-pass type I membrane protein. Secreted Synapse {ECO:0000250|UniProtKB:Q810C1} |
| Tissue Location | Expressed predominantly in the frontal lobe of the cerebral cortex of the brain. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Sequence variants in SLITRK1 are associated with Tourette's syndrome. Abelson JF, Kwan KY, O'Roak BJ, Baek DY, Stillman AA, Morgan TM, Mathews CA, Pauls DL, Rasin MR, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, Dure LS 4th, Kurlan R, Singer HS, Gilbert DL, Farhi A, Louvi A, Lifton RP, Sestan N, St Science. 2005 Oct 14;310(5746):317-20. PMID: 16224024
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