|Other Accession||NP_002214.2, 3709, 16439 (mouse), 81678 (rat)|
|Predicted||Human, Mouse, Rat, Dog, Cow|
|Calculated MW||308064 Da|
|Other Names||Inositol 1, 4, 5-trisphosphate receptor type 2, IP3 receptor isoform 2, IP3R 2, InsP3R2, Type 2 inositol 1, 4, 5-trisphosphate receptor, Type 2 InsP3 receptor, ITPR2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ITPR2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Isoform Short is found in skeletal muscle and heart|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
No cross-reactivity expected with other types of ITPR.
IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism. Futatsugi A, Nakamura T, Yamada MK, Ebisui E, Nakamura K, Uchida K, Kitaguchi T, Takahashi-Iwanaga H, Noda T, Aruga J, Mikoshiba K. Science. 2005 Sep 30;309(5744):2232-4. PMID: 16195467
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