ITPR3 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | Q14573 |
Other Accession | NP_002215.2, 3710 |
Predicted | Human, Mouse, Rat, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 304106 Da |
Gene ID | 3710 |
---|---|
Other Names | Inositol 1, 4, 5-trisphosphate receptor type 3, IP3 receptor isoform 3, IP3R 3, InsP3R3, Type 3 inositol 1, 4, 5-trisphosphate receptor, Type 3 InsP3 receptor, ITPR3 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ITPR3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ITPR3 |
---|---|
Function | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium (By similarity). Involved in cellular calcium ion homeostasis (PubMed:32949214). |
Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
Tissue Location | Expressed in intestinal crypt and villus epithelial cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
No cross-reactivity expected with other types of ITPR
References
IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism. Futatsugi A, Nakamura T, Yamada MK, Ebisui E, Nakamura K, Uchida K, Kitaguchi T, Takahashi-Iwanaga H, Noda T, Aruga J, Mikoshiba K. Science. 2005 Sep 30;309(5744):2232-4. PMID: 16195467
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