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EP1 receptor / PTGER1 Antibody (internal region)

Peptide-affinity purified goat antibody

  • IHC - EP1 receptor / PTGER1 Antibody (internal region) AF2501a
    AF2501a (2 µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P34995
Other Accession NP_000946.2, 5731
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 41801 Da
Additional Information
Gene ID 5731
Other Names Prostaglandin E2 receptor EP1 subtype, PGE receptor EP1 subtype, PGE2 receptor EP1 subtype, Prostanoid EP1 receptor, PTGER1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEP1 receptor / PTGER1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart
Research Areas
Citations (0)

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Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt. Han C, Wu T. J Biol Chem. 2005 Jun 24;280(25):24053-63. Epub 2005 Apr 26. PMID: 15855163

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$ 325.00
Cat# AF2501a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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