|Application ||IHC, E|
|Other Accession||NP_057419.2, 5625, 19125 (mouse)|
|Calculated MW||68002 Da|
|Other Names||Proline dehydrogenase 1, mitochondrial, 22.214.171.124, Proline oxidase, Proline oxidase 2, p53-induced gene 6 protein, PRODH, PIG6, POX2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PRODH Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Converts proline to delta-1-pyrroline-5-carboxylate.|
|Cellular Location||Mitochondrion matrix.|
|Tissue Location||Expressed in lung, skeletal muscle and brain, to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas|
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Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice. Paterlini M, Zakharenko SS, Lai WS, Qin J, Zhang H, Mukai J, Westphal KG, Olivier B, Sulzer D, Pavlidis P, Siegelbaum SA, Karayiorgou M, Gogos JA. Nat Neurosci. 2005 Nov;8(11):1586-94. Epub 2005 Oct 23. PMID: 16234811
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