|Other Accession||NP_000785.1, 1812, 13488 (mouse), 24316 (rat)|
|Predicted||Human, Mouse, Rat, Dog|
|Calculated MW||49293 Da|
|Other Names||D(1A) dopamine receptor, Dopamine D1 receptor, DRD1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Dopamine receptor D1 / DRD1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein Note=Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14.|
|Tissue Location||Detected in caudate, nucleus accumbens and in the olfactory tubercle.|
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Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens. Lee KW, Kim Y, Kim AM, Helmin K, Nairn AC, Greengard P. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3399-404. Epub 2006 Feb 21. PMID: 16492766
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