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Carabin / TBC1D10C Antibody (internal region)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IV04
Other Accession NP_940919.1, 374403, 108995 (mouse)
Predicted Human, Mouse, Rat, Pig, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 49712 Da
Additional Information
Gene ID 374403
Other Names Carabin, TBC1 domain family member 10C, TBC1D10C
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCarabin / TBC1D10C Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBC1D10C
Function Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.
Tissue Location Most abundant in spleen and peripheral blood leukocytes.
Research Areas
Citations (0)

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Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin. Pan F, Sun L, Kardian DB, Whartenby KA, Pardoll DM, Liu JO. Nature. 2007 Jan 25;445(7126):433-6. Epub 2007 Jan 17. PMID: 17230191

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$ 325.00
Cat# AF2563a
(40 western blots)
Availability: 7-10 days
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