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NGFRAP1 Antibody (C-Term)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q00994
Other Accession NP_996800.1, NP_996798.1, NP_055195.1, 27018
Predicted Human, Mouse, Rat
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 12959 Da
Additional Information
Gene ID 27018
Other Names Protein BEX3, Brain-expressed X-linked protein 3, Nerve growth factor receptor-associated protein 1, Ovarian granulosa cell 13.0 kDa protein HGR74, p75NTR-associated cell death executor, NGFRAP1, BEX3, DXS6984E, NADE
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNGFRAP1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BEX3, DXS6984E, NADE
Function May be a signaling adapter molecule involved in p75NTR- mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
Cellular Location Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity).
Tissue Location Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
Research Areas
Citations (0)

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This antibody is expected to recognise isoform a (NP_996800.1) and isoform b (NP_996798.1 and NP_055195.1).


Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR. Passino MA, Adams RA, Sikorski SL, Akassoglou K. Science. 2007 Mar 30;315(5820):1853-6. PMID: 17395831

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$ 325.00
Cat# AF2596a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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