|Other Accession||NP_006152.2, 4762, 18014 (mouse), 29410 (rat)|
|Predicted||Human, Mouse, Rat, Dog|
|Calculated MW||25718 Da|
|Other Names||Neurogenin-1, NGN-1, Class A basic helix-loop-helix protein 6, bHLHa6, Neurogenic basic-helix-loop-helix protein, Neurogenic differentiation factor 3, NeuroD3, NEUROG1, BHLHA6, NEUROD3, NGN, NGN1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Neurogenin 1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BHLHA6, NEUROD3, NGN, NGN1|
|Function||Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).|
|Tissue Location||Expression restricted to the embryonic nervous system|
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Association between the 5q31.1 gene neurogenin1 and schizophrenia. Fanous AH, Chen X, Wang X, Amdur RL, O'Neill FA, Walsh D, Kendler KS. Am J Med Genet B Neuropsychiatr Genet. 2007 Mar 5;144(2):207-14. PMID: 17044100
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