|Other Accession||NP_006152.2, 4762, 18014 (mouse), 29410 (rat)|
|Predicted||Human, Mouse, Rat, Dog|
|Calculated MW||25718 Da|
|Other Names||Neurogenin-1, NGN-1, Class A basic helix-loop-helix protein 6, bHLHa6, Neurogenic basic-helix-loop-helix protein, Neurogenic differentiation factor 3, NeuroD3, NEUROG1, BHLHA6, NEUROD3, NGN, NGN1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Neurogenin 1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BHLHA6, NEUROD3, NGN, NGN1|
|Function||Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).|
|Tissue Location||Expression restricted to the embryonic nervous system|
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Provided below are standard protocols that you may find useful for product applications.
Association between the 5q31.1 gene neurogenin1 and schizophrenia. Fanous AH, Chen X, Wang X, Amdur RL, O'Neill FA, Walsh D, Kendler KS. Am J Med Genet B Neuropsychiatr Genet. 2007 Mar 5;144(2):207-14. PMID: 17044100
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