|Other Accession||NP_060250.2, 55636, 320790 (mouse), 312974 (rat)|
|Predicted||Human, Mouse, Rat|
|Calculated MW||335927 Da|
|Other Names||Chromodomain-helicase-DNA-binding protein 7, CHD-7, 220.127.116.11, ATP-dependent helicase CHD7, CHD7, KIAA1416|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CHD7 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production.|
|Cellular Location||Isoform 1: Nucleus|
|Tissue Location||Widely expressed in fetal and adult tissues.|
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CHD7 gene polymorphisms are associated with susceptibility to idiopathic scoliosis. Gao X, Gordon D, Zhang D, Browne R, Helms C, Gillum J, Weber S, Devroy S, Swaney S, Dobbs M, Morcuende J, Sheffield V, Lovett M, Bowcock A, Herring J, Wise C. Am J Hum Genet. 2007 May;80(5):957-65. Epub 2007 Mar 12. PMID: 17436250
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