|Application ||WB, E|
|Other Accession||NP_001015049.1, NP_001015048.1, NP_004864.1, 9529|
|Calculated MW||51200 Da|
|Other Names||BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, BAG5, KIAA0873|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BAG5 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognise reported isoform a (NP_001015049.1) and isoform, b (NP_001015048.1; NP_004864.1).
BAG5 inhibits parkin and enhances dopaminergic neuron degeneration. Kalia SK, Lee S, Smith PD, Liu L, Crocker SJ, Thorarinsdottir TE, Glover JR, Fon EA, Park DS, Lozano AM. Neuron. 2004 Dec 16;44(6):931-45. PMID: 15603737
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